KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
26.67
Human Site:
S91
Identified Species:
41.9
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
S91
L
I
K
R
P
N
V
S
P
K
V
R
E
L
L
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
S91
L
I
K
R
P
N
V
S
P
K
V
R
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
S91
L
I
K
R
P
N
V
S
P
K
V
R
E
L
L
Dog
Lupus familis
XP_536242
380
42964
S91
L
I
K
R
P
N
V
S
P
K
V
R
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
S91
L
I
K
K
P
N
V
S
P
K
V
R
E
L
L
Rat
Rattus norvegicus
Q6AYK5
386
43662
S91
L
I
K
K
P
N
V
S
P
K
V
R
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
P91
I
M
K
K
A
N
I
P
P
K
V
R
E
I
L
Chicken
Gallus gallus
XP_420792
364
42082
N91
V
M
K
K
P
N
I
N
P
K
V
R
N
I
L
Frog
Xenopus laevis
NP_001086609
360
41600
S91
I
M
K
K
P
N
T
S
P
N
I
R
D
I
L
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
G91
A
V
S
R
P
D
V
G
S
E
L
Q
Q
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
K70
Q
S
Q
G
F
A
A
K
E
P
R
N
K
N
A
Honey Bee
Apis mellifera
XP_623803
246
28455
V35
T
A
P
F
L
T
C
V
D
C
L
K
D
F
R
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
E42
C
Q
L
V
Y
T
R
E
T
Y
K
D
H
V
K
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
N92
R
E
A
V
G
A
G
N
I
S
S
N
I
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
53.3
53.3
46.6
26.6
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
93.3
86.6
73.3
N.A.
13.3
20
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
7
14
7
0
0
0
0
0
0
0
7
% A
% Cys:
7
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
7
0
0
7
14
0
0
% D
% Glu:
0
7
0
0
0
0
0
7
7
7
0
0
47
0
0
% E
% Phe:
0
0
0
7
7
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
7
7
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
14
40
0
0
0
0
14
0
7
0
7
0
7
20
0
% I
% Lys:
0
0
60
34
0
0
0
7
0
54
7
7
7
7
7
% K
% Leu:
40
0
7
0
7
0
0
0
0
0
14
0
0
40
67
% L
% Met:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
60
0
14
0
7
0
14
7
7
7
% N
% Pro:
0
0
7
0
60
0
0
7
60
7
0
0
0
0
0
% P
% Gln:
7
7
7
0
0
0
0
0
0
0
0
7
7
0
0
% Q
% Arg:
7
0
0
34
0
0
7
0
0
0
7
60
0
0
7
% R
% Ser:
0
7
7
0
0
0
0
47
7
7
7
0
0
0
0
% S
% Thr:
7
0
0
0
0
14
7
0
7
0
0
0
0
0
0
% T
% Val:
7
7
0
14
0
0
47
7
0
0
54
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _